COMPANY NEWS
April 2025
New Study Demonstrates EVOs for EV Isolation and Purification
Researchers from the BIO-Processing Science & Innovation (BIOPSI) Lab, led by Truly co-founder James Lai, published a new study demonstrating the EVOs platform for rapid extracellular vesicle (EV) isolation. EVOs reduced sample volume 50-fold in under two hours, removed >99% of albumin, and preserved EV protein markers, miRNA cargo, and biological activity. When integrated upstream of size-exclusion chromatography, EVOs enabled 30 mL of conditioned medium to be processed through a 0.5 mL SEC column, producing EV preparations with purity reaching 3.6 × 10⁹ particles/µg protein. The results demonstrate EVOs' potential to simplify and scale EV research and bioprocessing workflows.
July 2024
Truly Completes NIH I-Corps Program
Truly team completes the 8-week National Institute of Health (NIH) Innovation Corps (I-Corps) program. Special thanks to external advisors John Hill (Affiliate Faculty at the University of Washington) and Harold Solomon (Principal at Georgia Tech Quadrant-i) for their participation.
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June 2022
UW CoMotion STEP Fund
Osmotic sample processor receives $25,000 UW CoMotion STEP Fund.
June 2022
Osmotic Processor Enables 100× Biomarker Enrichment for Rapid Diagnostics
Truly co-founders publish foundational demonstration of an osmosis-driven sample processing platform for improving point-of-care diagnostic sensitivity. The device spontaneously removed water at rates up to 15.2 mL/hour and concentrated dilute protein biomarkers by approximately 100-fold without pumps or an external power source.
Using commercial lateral flow assays, the processor concentrated 10 mL samples to approximately 100 µL, enabling detection of SARS-CoV-2 nucleocapsid protein that was initially below the assay's detection limit. Mass spectrometry independently measured an increase from 0.09 ± 0.06 µg/mL to 18.0 ± 4.3 µg/mL—nearly 200-fold enrichment. The work established the potential of osmotic sample preparation to enhance existing rapid diagnostic tests while maintaining a simple, equipment-free workflow.
February 2022
Truly Technologies LLC
OsmoProcessor LLC is now Truly Technologies, LLC.
July 2021
OsmoProcessor Completes NSF I-Corps Program
The OsmoProcessor team completed the National Science Foundation (NSF) I-Corps program supported by UW CoMotion and the Washington Entrepreneurial Research Evaluation & Commercialization Hub (WE-REACH), and received $2500 of customer discovery funding.
June 2021
OsmoProcessor, LLC Company Formation
OsmoProcessor, LLC was formed in Seattle, Washington, USA.
