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Truly Technologies has developed a simple and efficient bioprocessing solution to concentrate biomolecules at high yield and purity. Truly's technology uses osmotic pressure difference across a semipermeable membrane to simultaneously concentrate and purify biomolecules of interest. The technology can be applied to address a wide range of bioprocessing challenges from diagnostic assay biomarker concentration to therapeutic nanoparticle purification. 


Feature Highlights

Truly Technologies' biospecimen processor uses the osmotic pressure difference between a biofluid specimen and a polymer solution across a semipermeable membrane to simultaneously concentrate biomolecules of interest and remove unwanted sample content. The unique device design spreads the biofluid specimen into an ultra-thin fluid layer, enabling rapid diffusion of water molecules and small particles across the membrane. The membrane pore size can be selected to retain biomolecules of interest, and the device can be scaled to accommodate microliter-to-liter range of initial and final sample volumes. The device form factor can be tailored to specific use cases and sample collection mechanism can be easily integrated with downstream processes. Additionally, the concentration and purification process is performed spontaneously without a power source in just 3 simple steps.

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Innovative device design & optimized polymer formulation enables faster purification than traditional dialysis filtration approaches.

Doctors with Bacteriological Protection Suits


Simple design and processing workflow allows user to operate device with minimal training required.



Selectable membrane pore size and versatile device form factor allow reliable handling of different biomolecules and easy integration with other bioprocessing techniques.

Test Tubes


Rapid separation of biomolecules at low cost per sample without sacrificing yield and purity.

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Scalable device design that can be adjusted to process a wide range of sample volumes.


Chen S-Y, Wu AY, Lunde R, Lai JJ. Osmotic Processor for Enabling Sensitive and Rapid Biomarker Detection via Lateral Flow Assays. Frontiers in Bioengineering and Biotechnology. 2022;10. doi: 10.3389/fbioe.2022.884271.


“Highly interested in your product and looking forward to our collaboration."
- Director of Global Scientific Affairs at Diagnostics Assay Development Company

Work with Us

Contact us to discuss your application and try our bioprocessing solution!

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